AKT1 Ab
说明书

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AKT1 Ab
Western blot analysis of extracts from NIH/3T3 cells, treated with Insulin (0.01U/ml, 15mins), using Akt antibody.
AKT1 Ab
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using Akt antibody.
AKT1 Ab
Immunofluorescence analysis of HeLa cells, using Akt antibody.
AKT1 Ab
AKT1 Ab
AKT1 Ab
AKT1 Ab
AKT1 Ab
AKT1 Ab
AKT1 Ab
AKT1 Ab
AKT1 Ab

产品简介

产品简介

Catalog No.

AY0420

Source

Rabbit pAb

UniProt ID

P31749

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF

Calculated Mol Weight

56 kDa

Observed Mol Weight

56 kDa

Recommended Dilution

WB 1:500-1:1000

IHC 1:50-1:100

ICC/IF 1:50-1:200

IHF 1:50-1:100

Alternative Names

AKT, AKT1 kinase, C-AKT, EC 2.7.11.1, PKB, PKB-alpha, Protein kinase B, RAC, RAC-PK-alpha, RAC-alpha serine/threonine kinase, kinase Akt1

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human AKT1

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

An AGC kinase that plays a critical role in controlling the balance between survival and AP0ptosis. Phosphorylated and activated by PDK1 in the PI3 kinase pathway. Mediates survival signals downstream of PI3 kinase and several growth factor receptors by phosphorylating AP0pototic proteins. First found in a mouse transforming retrovirus.

引用文献

引用文献

Argirein alleviates vascular endothelial insulin resistance through suppressing the activation of Nox4-dependent O2- production in diabetic rats

期刊名称：

FREE RADICAL BIOLOGY AND MEDICINE

PMID：

29709706

影响因子：

6.02

应用范围：

WB,IHC

检测物种：

Rat

发表时间：

2018-04-27
Immunomodulatory activity of Ganoderma lucidum immunomodulatory protein via PI3K/Akt and MAPK signaling pathways in RAW264.7 cells

期刊名称：

JOURNAL OF CELLULAR PHYSIOLOGY

PMID：

31148200

影响因子：

4.522

应用范围：

WB

检测物种：

Mouse

发表时间：

2019-05-30
Immunostimulatory effects of the intracellular polysaccharides isolated from liquid culture of Ophiocordyceps sinensis (Ascomycetes) on RAW264.7 cells via the MAPK and PI3K/Akt signaling pathways

期刊名称：

JOURNAL OF ETHNOPHARMACOLOGY

PMID：

33892066

影响因子：

4.36

应用范围：

WB

检测物种：

Mouse

发表时间：

2021-04-20
Melatonin inhibits gallbladder cancer cell migration and invasion via ERK‑mediated induction of epithelial‑to‑mesenchymal transition

期刊名称：

Oncology Letters

PMID：

34188711

影响因子：

2.967

应用范围：

WB

检测物种：

Human

发表时间：

2021-06-15
Ethoxy-erianin phosphate and afatinib synergistically inhibit liver tumor growth and angiogenesis via regulating VEGF and EGFR signaling pathways

期刊名称：

TOXICOLOGY AND APPLIED PHARMACOLOGY

PMID：

35143806

影响因子：

4.46

应用范围：

WB

检测物种：

Mouse,Human

发表时间：

2022-02-07
Lignans from Eucommia ulmoides Oliver leaves exhibit neuroprotective effects via activation of the PI3K/Akt/GSK-3β/Nrf2 signaling pathways in H2O2-treated PC-12 cells

期刊名称：

PHYTOMEDICINE

PMID：

35487038

影响因子：

6.656

应用范围：

WB

检测物种：

Rat

发表时间：

2022-04-19

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AY0420

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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