p-WEE1 (S642) Ab
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p-WEE1 (S642) Ab
Western blot analysis of extracts from 293 cells, treated with etoposide (25uM, 60mins), using WEE1 (Phospho-Ser642) antibody.
p-WEE1 (S642) Ab
p-WEE1 (S642) Ab
p-WEE1 (S642) Ab
p-WEE1 (S642) Ab
p-WEE1 (S642) Ab
p-WEE1 (S642) Ab
p-WEE1 (S642) Ab
p-WEE1 (S642) Ab
p-WEE1 (S642) Ab
p-WEE1 (S642) Ab
p-WEE1 (S642) Ab

产品简介

产品简介

Catalog No.

AY0412

Source

Rabbit pAb

UniProt ID

P30291

Reactivity

Human;Mouse;Rat

Application

WB

Calculated Mol Weight

72 kDa

Observed Mol Weight

96 kDa

Recommended Dilution

WB 1:500-1:1000

Alternative Names

EC 2.7.10.2; kinase WEE1; Wee1-like protein kinase; WEE1A; WEE1hu

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human WEE1 around the phosphorylation site of S642

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Acts as a negative regulator of entry into mitosis (G2 to M transition) by protecting the nucleus from cytoplasmically activated cyclin B1-complexed CDK1 before the onset of mitosis by mediating phosphorylation of CDK1 on 'Tyr-15'.Specifically phosphorylates and inactivates cyclin B1-complexed CDK1 reaching a maximum during G2 phase and a minimum as cells enter M phase.

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AY0412

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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