Cleaved-Caspase 1 p20 Ab
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Cleaved-Caspase 1 p20 Ab
Western blot analysis of extracts from rat eye cells, using CASP1 (p20, Cleaved-Asn120) antibody.
Cleaved-Caspase 1 p20 Ab
Cleaved-Caspase 1 p20 Ab
Cleaved-Caspase 1 p20 Ab
Cleaved-Caspase 1 p20 Ab
Cleaved-Caspase 1 p20 Ab
Cleaved-Caspase 1 p20 Ab
Cleaved-Caspase 1 p20 Ab
Cleaved-Caspase 1 p20 Ab
Cleaved-Caspase 1 p20 Ab
Cleaved-Caspase 1 p20 Ab
Cleaved-Caspase 1 p20 Ab

产品简介

产品简介

Catalog No.

AY0406

Source

Rabbit pAb

UniProt ID

P29466

Reactivity

Human

Application

WB

Calculated Mol Weight

20,45 kDa

Observed Mol Weight

20, 45 kDa

Recommended Dilution

WB 1:500-1:1000

Alternative Names

CASP-1; caspase-1; EC 3.4.22.36; ICE; IL-1 beta converting enzyme; IL-1BC; IL1BCE; interleukin-1 beta convertase; interleukin-1 beta converting enzyme; p45

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Other

Immunogen

A synthesized peptide derived from human Caspase 1

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.

引用文献

引用文献

Regulation of NLRP3 inflammasome by CD38 through cADPR-mediated Ca2+ release in vascular smooth muscle cells in diabetic mice

期刊名称：

LIFE SCIENCES

PMID：

32407845

影响因子：

3.647

应用范围：

WB,IHC,ICC/IF

检测物种：

Mouse

发表时间：

2020-05-11
3,4,5-O-tricaffeoylquinic acid with anti-radiation activity suppresses LPS-induced NLRP3 inflammasome activation via autophagy in THP-1 macrophages

期刊名称：

MOLECULAR IMMUNOLOGY

PMID：

35633614

影响因子：

4.174

应用范围：

WB

检测物种：

Mouse,Human

发表时间：

2022-05-25
Sodium tanshinone IIA sulfonate ameliorates neointima by protecting endothelial progenitor cells in diabetic mice

期刊名称：

BMC Cardiovascular Disorders

PMID：

37697234

影响因子：

2.1

应用范围：

WB,ICC/IF,IP

检测物种：

Mouse

发表时间：

2023-09-11
Methylprednisolone alleviates lung injury in sepsis by regulating miR-151-5p/USP38 pathway

期刊名称：

INTERNATIONAL IMMUNOPHARMACOLOGY

PMID：

38944949

影响因子：

4.8

应用范围：

WB

检测物种：

Mouse

发表时间：

2024-06-29
Overexpression of NLRP12 enhances macrophage immune response and alleviates herpes simplex keratitis

期刊名称：

Frontiers in Cellular and Infection Microbiology

PMID：

39119293

影响因子：

4.6

应用范围：

WB

检测物种：

Mouse

发表时间：

2024-07-25

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AY0406

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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