Cleaved-Caspase 1 p20 Ab
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Cleaved-Caspase 1 p20 Ab
Western blot analysis of extracts from K562 cells and HepG2 cells, using Caspase 1 (Cleaved-Asp210) antibody
Cleaved-Caspase 1 p20 Ab
Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue, using Caspase 1 (Cleaved-Asp210) antibody
Cleaved-Caspase 1 p20 Ab
Cleaved-Caspase 1 p20 Ab
Cleaved-Caspase 1 p20 Ab
Cleaved-Caspase 1 p20 Ab
Cleaved-Caspase 1 p20 Ab
Cleaved-Caspase 1 p20 Ab
Cleaved-Caspase 1 p20 Ab
Cleaved-Caspase 1 p20 Ab
Cleaved-Caspase 1 p20 Ab
Cleaved-Caspase 1 p20 Ab

产品简介

产品简介

Catalog No.

AY0403

Source

Rabbit pAb

UniProt ID

P29466

Reactivity

Human

Application

WB;IHC

Calculated Mol Weight

20,45 kDa

Observed Mol Weight

20, 45 kDa

Recommended Dilution

WB 1:500-1:1000

IHC 1:50-1:100

Alternative Names

CASP-1, ICE, IL-1 beta converting enzyme, IL-1BC, IL1BCE, caspase-1, interleukin-1 beta convertase, interleukin-1 beta converting enzyme, p45

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Other

Immunogen

A synthesized peptide derived from human Caspase 1

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.

引用文献

引用文献

Antidepressant effects of total alkaloids of Fibraurea recisa on improving corticosterone-induced apoptosis of HT-22 cells and chronic unpredictable mild stress-induced depressive-like behaviour in mice

期刊名称：

PHARMACEUTICAL BIOLOGY

PMID：

35938494

影响因子：

3.889

应用范围：

WB

检测物种：

Mouse

发表时间：

2022-08-07

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AY0403

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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