p-Integrin beta 4 (Y1510) Ab - 上海埃必威生物技术有限公司

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p-Integrin beta 4 (Y1510) Ab

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Western blot analysis of extracts from HepG2 cells, treated with Na2VO3 (0.3nM, 40mins), using ITGB4 (Phospho-Tyr1510) antibody.

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using ITGB4 (Phospho-Tyr1510) antibody.

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产品简介

Catalog No.

AY0329

Source

Rabbit pAb

UniProt ID

P16144

Reactivity

Human;Mouse;Rat

Application

WB;IHC

Calculated Mol Weight

202 kDa

Observed Mol Weight

202 kDa

Recommended Dilution

WB 1:500-1:1000

IHC 1:50-1:100

Alternative Names

CD104 antigen, GP150, ITB4, integrin beta-4, integrin beta-4C

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human Integrin beta 4 around the phosphorylation site of Y1510

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Purification

Affinity-chromatography

Concentration

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Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling.

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AY0329

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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