SIN3B Ab
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SIN3B Ab
Western blot analysis of extracts from A549 cells, using SIN3B antibody.
SIN3B Ab
Immunofluorescence analysis of HeLa cells, using SIN3B antibody.
SIN3B Ab
SIN3B Ab
SIN3B Ab
SIN3B Ab
SIN3B Ab
SIN3B Ab
SIN3B Ab
SIN3B Ab
SIN3B Ab
SIN3B Ab

产品简介

产品简介

Catalog No.

AY0164

Source

Rabbit pAb

UniProt ID

O75182

Reactivity

Human

Application

WB;ICC/IF

Calculated Mol Weight

133 kDa

Observed Mol Weight

133 kDa

Recommended Dilution

WB 1:500-1:1000

ICC/IF 1:50-1:200

Alternative Names

Paired amphipathic helix protein Sin3b, Transcriptional corepressor Sin3b, Histone deacetylase complex subunit Sin3b, SIN3B, KIAA0700

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human SIN3B

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription. With FOXK1, regulates cell cycle progression probably by repressing cell cycle inhibitor genes expression.

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AY0164

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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