SMAD3 Ab
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SMAD3 Ab
Western blot analysis of Smad3 in 293T,Jurkat,Rat Heart,Mouse Heart lysates using Smad3 (4H4) antibody.
SMAD3 Ab
Immunohistochemistry analysis of paraffinembedded Human Liver Tissue using Smad3 antibody.
SMAD3 Ab
Immunohistochemistry analysis of paraffinembedded Human Colon Carcinoma using Smad3 antibody.
SMAD3 Ab
SMAD3 Ab
SMAD3 Ab
SMAD3 Ab
SMAD3 Ab
SMAD3 Ab
SMAD3 Ab
SMAD3 Ab
SMAD3 Ab

产品简介

产品简介

Catalog No.

AB3639

Source

Mouse mAb

UniProt ID

P84022

Reactivity

Human;Mouse;Rat

Application

WB;IHC

Calculated Mol Weight

48 kDa

Observed Mol Weight

50 kDa

Recommended Dilution

WB 1:500-1:1000

IHC 1:50-1:100

Alternative Names

SMAD3; MADH3; Mothers against decapentaplegic homolog 3; MAD homolog 3; Mad3; Mothers against DPP homolog 3; hMAD-3; JV15-2; SMAD family member 3; SMAD 3; Smad3; Hsmad3

Host

Mouse

Isotype

Mouse IgG1

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human SMAD3

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Purification

Affinity-chromatography

Concentration

Buffer System

Mouse IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD3/SMAD4 complex, activates transcription. Also can form a SMAD3/SMAD4/JUN/FOS complex at the AP-1/SMAD site to regulate TGF-beta-mediated transcription.

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AB3639

规格：

20μl, 50μl, 100μl

价格：

¥700/20μl, ¥1400/50μl, ¥2500/100μl

货期：

3-4天

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