MSH6 Ab
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MSH6 Ab
MSH6 Ab
MSH6 Ab
MSH6 Ab
MSH6 Ab
MSH6 Ab
MSH6 Ab
MSH6 Ab
MSH6 Ab
MSH6 Ab
MSH6 Ab
MSH6 Ab

产品简介

产品简介

Catalog No.

AB3486

Source

Mouse mAb

UniProt ID

P52701

Reactivity

Human

Application

WB;IHC;ICC/IF;IHF;FC

Calculated Mol Weight

153 kDa

Observed Mol Weight

160 kDa

Recommended Dilution

WB 1:500-1:1000

IHC 1:50-1:100

ICC/IF 1:50-1:200

IHF 1:50-1:100

FC 1:20-1:100

Alternative Names

MSH6; GTBP; DNA mismatch repair protein Msh6; hMSH6; G/T mismatch-binding protein; GTBP; GTMBP; MutS-alpha 160 kDa subunit; p160

Host

Mouse

Isotype

Mouse IgG2a

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human MSH6

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Purification

Affinity-chromatography

Concentration

Buffer System

Mouse IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS alpha, which binds to DNA mismatches thereby initiating DNA repair. When bound, MutS alpha bends the DNA helix and shields approximately 20 base pairs, and recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA.

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AB3486

规格：

20μl, 50μl, 100μl

价格：

¥700/20μl, ¥1400/50μl, ¥2500/100μl

货期：

3-4天

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