MLH1 Ab
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MLH1 Ab
Western blot detection of MLH1 in SW48,293T,Jurkat and Hela cell lysates using MLH1 mouse mAb (1:500 diluted).Predicted band size:85KDa.Observed band size:85KDa.
MLH1 Ab
Immunocytochemistry staining of HeLa cells fixed in 1% Paraformaldehyde and using MLH1 mouse mAb (dilution 1:100).
MLH1 Ab
MLH1 Ab
MLH1 Ab
MLH1 Ab
MLH1 Ab
MLH1 Ab
MLH1 Ab
MLH1 Ab
MLH1 Ab
MLH1 Ab

产品简介

产品简介

Catalog No.

AB3426

Source

Mouse mAb

UniProt ID

P40692

Reactivity

Human;Monkey

Application

WB;ICC/IF

Calculated Mol Weight

85 kDa

Observed Mol Weight

85 kDa

Recommended Dilution

WB 1:500-1:1000

ICC/IF 1:50-1:200

Alternative Names

FCC2; COCA2; HNPCC

Host

Mouse

Isotype

Mouse IgG1

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human MLH1

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Purification

Affinity-chromatography

Concentration

Buffer System

Mouse IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Heterodimerizes with PMS2 to form MutL alpha, a component of the post-replicative DNA mismatch repair system (MMR). DNA repair is initiated by MutS alpha (MSH2-MSH6) or MutS beta (MSH2-MSH3) binding to a dsDNA mismatch, then MutL alpha is recruited to the heteroduplex. Assembly of the MutL-MutS-heteroduplex ternary complex in presence of RFC and PCNA is sufficient to activate endonuclease activity of PMS2.

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AB3426

规格：

20μl, 50μl, 100μl

价格：

¥700/20μl, ¥1400/50μl, ¥2500/100μl

货期：

3-4天

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