beta Arrestin 1 Ab
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beta Arrestin 1 Ab
Western blot detection of β-Arrestin 1 in K562 and Hela cell lysates using β-Arrestin 1 mouse mAb(dilution 1:500).Predicted band size:51kDa.Observed band size:51kDa.
beta Arrestin 1 Ab
beta Arrestin 1 Ab
beta Arrestin 1 Ab
beta Arrestin 1 Ab
beta Arrestin 1 Ab
beta Arrestin 1 Ab
beta Arrestin 1 Ab
beta Arrestin 1 Ab
beta Arrestin 1 Ab
beta Arrestin 1 Ab
beta Arrestin 1 Ab

产品简介

产品简介

Catalog No.

AB3380

Source

Mouse mAb

UniProt ID

P49407

Reactivity

Human

Application

WB

Calculated Mol Weight

47 kDa

Observed Mol Weight

51 kDa

Recommended Dilution

WB 1:500-1:1000

Alternative Names

ARB1; ARR1; ARRB1; Arrestin 2; Arrestin beta 1; Arrestin beta-1; Beta-arrestin-1.

Host

Mouse

Isotype

Mouse IgG2b

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human beta Arrestin 1

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Purification

Affinity-chromatography

Concentration

Buffer System

Mouse IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta-arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation.

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AB3380

规格：

20μl, 50μl, 100μl

价格：

¥700/20μl, ¥1400/50μl, ¥2500/100μl

货期：

3-4天

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