MEK6 Ab
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MEK6 Ab
Western blot analysis of extracts from PC12,C6,Ramos,Jurkat and Hela cell lysates using MKK3/6 mouse mAb (1:1000 diluted).Predicted band size:40KDa.Observed band size:40KDa.
MEK6 Ab
Immunoprecipitation analysis of Hela cell lysates using MKK3/6 mouse mAb.
MEK6 Ab
MEK6 Ab
MEK6 Ab
MEK6 Ab
MEK6 Ab
MEK6 Ab
MEK6 Ab
MEK6 Ab
MEK6 Ab
MEK6 Ab

产品简介

产品简介

Catalog No.

AB3351

Source

Mouse mAb

UniProt ID

P52564

Reactivity

Human;Rat

Application

WB;IP

Calculated Mol Weight

37 kDa

Observed Mol Weight

40 kDa

Recommended Dilution

WB 1:500-1:1000

IP 1:20-1:50

Alternative Names

MEK6; MKK6; MAPKK6; PRKMK6; SAPKK3; MAP2K6;

Host

Mouse

Isotype

Mouse IgG1

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human MEK6

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Purification

Affinity-chromatography

Concentration

Buffer System

Mouse IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. With MAP3K3/MKK3, catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinases p38 MAPK11, MAPK12, MAPK13 and MAPK14 and plays an important role in the regulation of cellular responses to cytokines and all kinds of stresses.

引用文献

引用文献

Gamma synuclein promotes cancer metastasis through the MKK3/6-p38MAPK cascade

期刊名称：

International Journal of Biological Sciences

PMID：

35637967

影响因子：

10.75

应用范围：

WB

检测物种：

Human

发表时间：

2022-05-01

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AB3351

规格：

20μl, 50μl, 100μl

价格：

¥700/20μl, ¥1400/50μl, ¥2500/100μl

货期：

3-4天

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