p-Histone H2A.X (S139) Ab
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p-Histone H2A.X (S139) Ab
Western blot detection of Phosphorylation of H2A.X at Serine 139 in 3T3 or Hydroxyurea-treated 3T3 cell lysates using Phospho-Histone H2A.X (Ser139) mouse mAb (1:1000 diluted).Predicted band size:15KDa.Observed band size:15KDa.
p-Histone H2A.X (S139) Ab
Immunofluorescent analysis of Phosphorylation of H2A.X at Serine 139 in A549(upper,untreated or Hydroxyurea-treated) and Hela(lower,untreated or Hydroxyurea-treated) using Phospho-Histone H2A.X (Ser139) mouse mAb (1:200).
p-Histone H2A.X (S139) Ab
p-Histone H2A.X (S139) Ab
p-Histone H2A.X (S139) Ab
p-Histone H2A.X (S139) Ab
p-Histone H2A.X (S139) Ab
p-Histone H2A.X (S139) Ab
p-Histone H2A.X (S139) Ab
p-Histone H2A.X (S139) Ab
p-Histone H2A.X (S139) Ab
p-Histone H2A.X (S139) Ab

产品简介

产品简介

Catalog No.

AB3322

Source

Mouse mAb

UniProt ID

Reactivity

Human;Mouse

Application

WB;ICC/IF

Calculated Mol Weight

15 kDa

Observed Mol Weight

15 kDa

Recommended Dilution

WB 1:500-1:1000

ICC/IF 1:50-1:200

Alternative Names

H2A histone family, member X;H2A.X;H2a/x;H2AFX;H2AX;H2AX histone;H2AX_HUMAN;Histone H2A.X;Histone H2AX

Host

Mouse

Isotype

Mouse IgG2a

Clonality

Monoclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human Histone H2A.X around the phosphorylation site of S139

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Purification

Affinity-chromatography

Concentration

Buffer System

Mouse IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.

引用文献

引用文献

Elevating H3K27me3 level sensitizes colorectal cancer to oxaliplatin

期刊名称：

Journal of Molecular Cell Biology

PMID：

31065671

影响因子：

4.671

应用范围：

ICC/IF

检测物种：

Human

发表时间：

2019-05-08
HMGA1 promotes the progression of esophageal squamous cell carcinoma by elevating TKT-mediated upregulation of pentose phosphate pathway

期刊名称：

Cell Death & Disease

PMID：

39080260

影响因子：

8.1

应用范围：

ICC/IF,WB,IHC

检测物种：

Human,Mouse

发表时间：

2024-07-30

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AB3322

规格：

20μl, 50μl, 100μl

价格：

¥700/20μl, ¥1400/50μl, ¥2500/100μl

货期：

3-4天

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