Caspase 9 Ab
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Caspase 9 Ab
Western blot detection of Caspase-9 in A549,MCF7,Jurkat,K562 and Hela cell lysates using Caspase-9 mouse mAb (1:1000 diluted).Predicted band size:49/37KDa.Observed band size:49KDa.
Caspase 9 Ab
Caspase 9 Ab
Caspase 9 Ab
Caspase 9 Ab
Caspase 9 Ab
Caspase 9 Ab
Caspase 9 Ab
Caspase 9 Ab
Caspase 9 Ab
Caspase 9 Ab
Caspase 9 Ab

产品简介

产品简介

Catalog No.

AB3290

Source

Mouse mAb

UniProt ID

P55211

Reactivity

Human

Application

WB

Calculated Mol Weight

46 kDa

Observed Mol Weight

49, 37 kDa

Recommended Dilution

WB 1:500-1:1000

Alternative Names

APAF-3; ICE-LAP6; Apoptotic protease Mch-6; Apoptotic protease activating factor 3; CASP-9; Caspase-9 precursor; ICE-like apoptotic protease 6; MCH6; RNCASP9

Host

Mouse

Isotype

Mouse IgG1

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human Caspase 9

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Purification

Affinity-chromatography

Concentration

Buffer System

Mouse IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates effector caspases caspase-3 (CASP3) or caspase-7 (CASP7). Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).

引用文献

引用文献

CXCL3 overexpression affects the malignant behavior of oral squamous cell carcinoma cells via the MAPK signaling pathway

期刊名称：

JOURNAL OF ORAL PATHOLOGY & MEDICINE

PMID：

34392586

影响因子：

4.253

应用范围：

WB

检测物种：

Human

发表时间：

2021-08-15

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AB3290

规格：

20μl, 50μl, 100μl

价格：

¥700/20μl, ¥1400/50μl, ¥2500/100μl

货期：

3-4天

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