DR5 Ab
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DR5 Ab
Western blot detection of DR5 in SW480,K562,HCT116 and Hela cell lysates using DR5 mouse mAb (1:1000 diluted).Predicted band size:40/48KDa.Observed band size:40/48KDa.
DR5 Ab
DR5 Ab
DR5 Ab
DR5 Ab
DR5 Ab
DR5 Ab
DR5 Ab
DR5 Ab
DR5 Ab
DR5 Ab
DR5 Ab

产品简介

产品简介

Catalog No.

AB3253

Source

Mouse mAb

UniProt ID

O14763

Reactivity

Human

Application

WB

Calculated Mol Weight

48 kDa

Observed Mol Weight

40, 48 kDa

Recommended Dilution

WB 1:500-1:1000

Alternative Names

Death receptor 5; TRAIL receptor 2; TRAIL-R2; CD262; TNFRSF10B; DR5; KILLER; TRAILR2; TRICK2; ZTNFR9;

Host

Mouse

Isotype

Mouse IgG2b

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human DR5

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Purification

Affinity-chromatography

Concentration

Buffer System

Mouse IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Receptor for the cytotoxic ligand TNFSF10/TRAIL.The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.

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AB3253

规格：

20μl, 50μl, 100μl

价格：

¥700/20μl, ¥1400/50μl, ¥2500/100μl

货期：

3-4天

订购信息：

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