DR5 Ab
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DR5 Ab
Western blot detection of DR5 in Mouse kindey,Mouse brain,HCT116 and Hela cell lysates using DR5 mouse mAb (1:500-1:1000 diluted).Predicted band size:40/48KDa.Observed band size:40/48KDa.
DR5 Ab
Immunofluorescent analysis of HeLa cells fixed by Paraformaldehyde and using DR5 mouse mAb diluted 1:100.
DR5 Ab
DR5 Ab
DR5 Ab
DR5 Ab
DR5 Ab
DR5 Ab
DR5 Ab
DR5 Ab
DR5 Ab
DR5 Ab

产品简介

产品简介

Catalog No.

AB3251

Source

Mouse mAb

UniProt ID

O14763

Reactivity

Human;Mouse

Application

WB;ICC/IF

Calculated Mol Weight

48 kDa

Observed Mol Weight

48 kDa

Recommended Dilution

WB 1:500-1:1000

ICC/IF 1:50-1:200

Alternative Names

Death receptor 5; TRAIL receptor 2; TRAIL-R2; CD262; TNFRSF10B; DR5; KILLER; TRAILR2; TRICK2; ZTNFR9;

Host

Mouse

Isotype

Mouse IgG1

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human DR5

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Purification

Affinity-chromatography

Concentration

Buffer System

Mouse IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Receptor for the cytotoxic ligand TNFSF10/TRAIL.The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.

引用文献

引用文献

Vimentin, inversely correlating with infiltration of CD8 + T lymphocytes, promotes nuclear translocation of PD-L1 in esophageal squamous cell carcinoma

期刊名称：

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

PMID：

38901494

影响因子：

4.6

应用范围：

IHC

检测物种：

Mouse

发表时间：

2024-06-18

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AB3251

规格：

20μl, 50μl, 100μl

价格：

¥700/20μl, ¥1400/50μl, ¥2500/100μl

货期：

3-4天

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