Cyclin H Ab

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Cyclin H Ab
Western blot detection of Cyclin H in Jurkat,K562 and A431 cell lysates using Cyclin H mouse mAb (1:1000 diluted).Predicted band size: 38KDa.Observed band size: 38KDa.
Cyclin H Ab
Immunoprecipitation analysis of Hela cell lysates using Cyclin H mouse mAb.
Cyclin H Ab
Cyclin H Ab
Cyclin H Ab
Cyclin H Ab
Cyclin H Ab
Cyclin H Ab
Cyclin H Ab
Cyclin H Ab
Cyclin H Ab
Cyclin H Ab

产品简介

产品简介

Catalog No.

AB3185

Source

Mouse mAb

UniProt ID

Reactivity

Human

Application

WB;IP

Calculated Mol Weight

38 kDa

Observed Mol Weight

38 kDa

Recommended Dilution

WB 1:500-1:1000

IP 1:20-1:50

Alternative Names

CAK; CCNH; CDK-activating kinase; cyclin H; cyclin-dependent kinase-activating kinase; Cyclin-H; MO15-associated protein; p34; p37;

Host

Mouse

Isotype

Mouse IgG2b

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human Cyclin H

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Purification

Affinity-chromatography

Concentration

Buffer System

Mouse IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.

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AB3185

规格:

20μl, 50μl, 100μl

价格:

¥700/20μl, ¥1400/50μl, ¥2500/100μl

货期:

3-4天

订购信息:

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