CRTC1 Ab
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CRTC1 Ab
Western blot detection of MECT1 / Torc1 in Hela and Jurkat lysates using MECT1 / Torc1 mouse mAb (1:1000 diluted).Predicted band size: 78KDa.Observed band size: 78KDa.
CRTC1 Ab
Immunofluorescent analysis stain of Hela using MECT1 / Torc1 mouse mAb (1:200).
CRTC1 Ab
Immunoprecipitation analysis of Hela cell lysate using MECT1 / Torc1 mouse mAb.
CRTC1 Ab
Flow Cytometry analysis of K562 cells stained with TORC1(N-terminus) (red, 1/100 dilution), followed by FITC-conjugated goat anti-mouse IgG. Blue line histogram represents the isotype control, normal mouse IgG.
CRTC1 Ab
CRTC1 Ab
CRTC1 Ab
CRTC1 Ab
CRTC1 Ab
CRTC1 Ab
CRTC1 Ab
CRTC1 Ab

产品简介

产品简介

Catalog No.

AB3184

Source

Mouse mAb

UniProt ID

Q6UUV9

Reactivity

Human

Application

WB;ICC/IF;IP;FC

Calculated Mol Weight

67 kDa

Observed Mol Weight

78 kDa

Recommended Dilution

WB 1:500-1:1000

ICC/IF 1:50-1:200

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

CREB regulated transcription coactivator 1; CRTC1; MECT 1;Mucoepidermoid carcinoma translocated 1; TORC1;Transducer of CREB protein 1;

Host

Mouse

Isotype

Mouse IgG2b

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human CRTC1

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Purification

Affinity-chromatography

Concentration

Buffer System

Mouse IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells.

引用文献

引用文献

Shexiang Tongxin Dropping Pills Promote Macrophage Polarization-Induced Angiogenesis Against Coronary Microvascular Dysfunction via PI3K/Akt/mTORC1 Pathway

期刊名称：

Frontiers in Pharmacology

PMID：

35401214

影响因子：

5.988

应用范围：

ICC/IF,WB

检测物种：

Rat,Human

发表时间：

2022-03-23

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AB3184

规格：

20μl, 50μl, 100μl

价格：

¥700/20μl, ¥1400/50μl, ¥2500/100μl

货期：

3-4天

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