GSK 3 beta Ab
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GSK 3 beta Ab
Western blot analysis of extracts from A549, Hela, 3T3 and Rat Brain cell lysates using GSK-3β mouse mAb(1:1000 diluted).Predicted band size:46KDa.Observed band size:46KDa.
GSK 3 beta Ab
Immunofluorescent analysis of HeLa cells fixed with -20℃ Methanol and using GSK-3β mouse mAb (dilution 1:200).
GSK 3 beta Ab
Immunoprecipitation analysis of Hela cell lysates using GSK-3β.GSK-3β Rabbit mAb was used for the western blot analysis (1:1000 diluted).
GSK 3 beta Ab
GSK 3 beta Ab
GSK 3 beta Ab
GSK 3 beta Ab
GSK 3 beta Ab
GSK 3 beta Ab
GSK 3 beta Ab
GSK 3 beta Ab
GSK 3 beta Ab

产品简介

产品简介

Catalog No.

AB3168

Source

Mouse mAb

UniProt ID

P49841

Reactivity

Human;Mouse

Application

WB;ICC/IF;IP

Calculated Mol Weight

47 kDa

Observed Mol Weight

46 kDa

Recommended Dilution

WB 1:500-1:1000

ICC/IF 1:50-1:200

IP 1:20-1:50

Alternative Names

Glycogen Synthase Kinase 3 Beta; Glycogen synthase kinase-3 beta; GSK 3 beta; GSK-3 beta; GSK3B; GSK3beta isoform;

Host

Mouse

Isotype

Mouse IgG2a

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human GSK 3 beta

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Purification

Affinity-chromatography

Concentration

Buffer System

Mouse IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), EIF2B, CTNNB1/beta-catenin, APC, AXIN1, DPYSL2/CRMP2, JUN, NFATC1/NFATC, MAPT/TAU and MACF1.Requires primed phosphorylation of the majority of its substrates.

引用文献

引用文献

Inhibition of pyruvate dehydrogenase kinase improves carbohydrate utilization in Nile tilapia by regulating PDK2/4-PDHE1α axis and insulin sensitivity

期刊名称：

Animal Nutrition

PMID：

36016966

影响因子：

5.285

应用范围：

WB

检测物种：

Fish

发表时间：

2022-06-24
The AMPK and AKT/GSK3β pathways are involved in recombinant proteins fibroblast growth factor 1 (rFGF1 and rFGF1a) improving glycolipid metabolism in rainbow trout (Oncorhynchus mykiss) fed a high carbohydrate diet

期刊名称：

Animal Nutrition

PMID：

38444689

影响因子：

6.1

应用范围：

WB

检测物种：

Fish

发表时间：

2024-01-03

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AB3168

规格：

20μl, 50μl, 100μl

价格：

¥700/20μl, ¥1400/50μl, ¥2500/100μl

货期：

3-4天

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