TIF1 beta Ab
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TIF1 beta Ab
Western blot detection of KAP1 / TIF1 beta in 293T and HepG2 cell lysates using KAP1 / TIF1 beta mouse mAb (1:1000 diluted).Observed band size: 110KDa.
TIF1 beta Ab
IHC of paraffin-embedded human Spleen using anti-KAP1 / TIF1 beta diluted 1/50-1/100.
TIF1 beta Ab
Immunofluorescent analysis of HeLa cells fixed with 4% Paraformaldehyde and using anti-KAP1 / TIF1 beta mouse mAb (dilution 1:100).
TIF1 beta Ab
Immunoprecipitation analysis of Hela cell lysates using KAP1 / TIF1 beta mouse mAb.
TIF1 beta Ab
TIF1 beta Ab
TIF1 beta Ab
TIF1 beta Ab
TIF1 beta Ab
TIF1 beta Ab
TIF1 beta Ab
TIF1 beta Ab

产品简介

产品简介

Catalog No.

AB3132

Source

Mouse mAb

UniProt ID

Q13263

Reactivity

Human

Application

WB;IHC;ICC/IF;IHF;IP

Calculated Mol Weight

89 kDa

Observed Mol Weight

110 kDa

Recommended Dilution

WB 1:500-1:1000

IHC 1:50-1:100

ICC/IF 1:50-1:200

IHF 1:50-1:100

IP 1:20-1:50

Alternative Names

E3 SUMO-protein ligase TRIM28; KRAB-associated protein 1; KAP-1; KRAB-interacting protein 1; KRIP-1; Nuclear corepressor KAP-1; KAP1; TF1B; RNF96; TIF1B; TRIM28;

Host

Mouse

Isotype

Mouse IgG1

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human TIF1 beta

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Purification

Affinity-chromatography

Concentration

Buffer System

Mouse IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression.

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AB3132

规格：

20μl, 50μl, 100μl

价格：

¥700/20μl, ¥1400/50μl, ¥2500/100μl

货期：

3-4天

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