KEAP1 Ab
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KEAP1 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
KEAP1 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
KEAP1 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
KEAP1 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
KEAP1 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
KEAP1 Ab

Immunofluorescent analysis using the Antibody at 1:25 dilution.

KEAP1 Ab
Immunofluorescent analysis using the Antibody at 1:100 dilution.
KEAP1 Ab
KEAP1 Ab
KEAP1 Ab
KEAP1 Ab
KEAP1 Ab

产品简介

产品简介

Catalog No.

CY8804

Source

Recombinant Rabbit mAb

UniProt ID

Reactivity

Human;Mouse;Rat

Application

WB;ICC/IF

Calculated Mol Weight

70 kDa

Observed Mol Weight

60-64 kDa

Recommended Dilution

WB 1:1000-1:2000

ICC/IF 1:50-1:100

Alternative Names

Kelch-like ECH-associated protein 1;Cytosolic inhibitor of Nrf2;Kelch-like protein 19;INRF2;KIAA0132;KLHL19

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human KEAP1

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that regulates the response to oxidative stress by targeting NFE2L2/NRF2 for ubiquitination.KEAP1 acts as a key sensor of oxidative and electrophilic stress: in normal conditions, the BCR(KEAP1) complex mediates ubiquitination and degradation of NFE2L2/NRF2, a transcription factor regulating expression of many cytoprotective genes.

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CY8804

规格:

20μl, 50μl, 100μl

价格:

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期:

现货

订购信息:

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