xCT Ab
TOP200
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xCT Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
xCT Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
xCT Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
xCT Ab
Western blot analysis of xCT expression in (1) HepG2 cell lysate; (2) Mouse brain lysate.
xCT Ab
Immunofluorescent analysis using the Antibody at 1:50 dilution.
xCT Ab
Immunofluorescent analysis using the Antibody at 1:50 dilution.
xCT Ab
Immunofluorescent analysis using the Antibody at 1:150 dilution.
xCT Ab
Immunofluorescent analysis using the Antibody at 1:150 dilution.
xCT Ab
xCT Ab
xCT Ab
xCT Ab

产品简介

产品简介

Catalog No.

CY7046

Source

Recombinant Rabbit mAb

UniProt ID

Q9UPY5

Reactivity

Human;Mouse;Rat

Application

WB;ICC/IF;IP

Calculated Mol Weight

55 kDa

Observed Mol Weight

55 kDa

Recommended Dilution

WB 1:1000-1:2000

ICC/IF 1:50-1:200

IP 1:20-1:50

Alternative Names

CCBR1; Cysteine/glutamate transporter; SLC7A11; solute carrier family 7; xCT;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human xCT

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Heterodimer with SLC3A2, that functions as an antiporter by mediating the exchange of extracellular anionic L-cystine and intracellular L-glutamate across the cellular plasma membrane.Provides L-cystine for the maintenance of the redox balance between extracellular L-cystine and L-cysteine and for the maintenance of the intracellular levels of glutathione that is essential for cells protection from oxidative stress.

引用文献

引用文献

Panaxynol from dietary sources modulates ferroptosis through ceRNA networks in synovium: a novel strategy for alleviating rheumatoid arthritis through functional food intervention

期刊名称：

Food & Function

PMID：

40304116

影响因子：

5.1

应用范围：

WB

检测物种：

Rat

发表时间：

2025-04-27
Cold atmospheric plasma drives USP49/HDAC3 axis mediated ferroptosis as a novel therapeutic strategy in endometrial cancer via reinforcing lactylation dependent p53 expression

期刊名称：

Journal of Translational Medicine

PMID：

40234906

影响因子：

6.1

应用范围：

WB

检测物种：

Human,Mouse

发表时间：

2025-04-15
Dietary Limonin ameliorates heart failure with preserved ejection fraction by targeting ferroptosis via modulation of the Nrf2/SLC7A11/GPX4 axis: An integrated transcriptomics and metabolomics analysis

期刊名称：

Food & Function

PMID：

40230319

影响因子：

5.1

应用范围：

WB,ICC/IF

检测物种：

Mouse

发表时间：

2025-03-31
The protective role of cannabidiol in stress-induced liver injury: modulating oxidative stress and mitochondrial damage

期刊名称：

Frontiers in Pharmacology

PMID：

40160456

影响因子：

4.4

应用范围：

WB

检测物种：

Mouse

发表时间：

2025-03-14
Sodium aescinate-induced hepatotoxicity via ATF4/GSH/GPX4 axis-mediated ferroptosis

期刊名称：

Scientific Reports

PMID：

39774712

影响因子：

3.8

应用范围：

WB;ICC/IF

检测物种：

Human,Mouse

发表时间：

2025-01-07
Stress-mediated Activation of Ferroptosis, Pyroptosis, and Apoptosis Following Mild Traumatic Brain Injury Exacerbates Neurological Dysfunctions

期刊名称：

MOLECULAR NEUROBIOLOGY

PMID：

39388040

影响因子：

4.6

应用范围：

ICC/IF,WB

检测物种：

Mouse

发表时间：

2024-10-10

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CY7046

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

现货

订购信息：

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