FBXO2 Ab
开学促销
说明书

一键复制产品信息

FBXO2 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
FBXO2 Ab
FBXO2 Ab
FBXO2 Ab
FBXO2 Ab
FBXO2 Ab
FBXO2 Ab
FBXO2 Ab
FBXO2 Ab
FBXO2 Ab
FBXO2 Ab
FBXO2 Ab

产品简介

产品简介

Catalog No.

BY2774

Source

Rabbit pAb

UniProt ID

Q9UK22

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF;IP;FC

Calculated Mol Weight

33 kDa

Observed Mol Weight

40 kDa

Recommended Dilution

WB 1:1000-1:5000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:10-1:200

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

F-box only protein 2;FBX2

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human FBXO2

点击查询

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Involved in the endoplasmic reticulum-associated degradation pathway (ERAD) for misfolded lumenal proteins by recognizing and binding sugar chains on unfolded glycoproteins that are retrotranslocated into the cytosol and promoting their ubiquitination and subsequent degradation. Prevents formation of cytosolic aggregates of unfolded glycoproteins that have been retrotranslocated into the cytosol. Able to recognize and bind denatured glycoproteins, preferentially those of the high-mannose type.

引用文献

引用文献

暂无数据

用户反馈

用户反馈

用户评论
用户名：
评论内容：
评论时间：
回复内容:
回复时间：
上一页
下一页
页码：
总页数：
总行数：
首页
尾页
BY2774

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

现货

订购信息：

您可以联系授权经销商购买Abways产品以及获得技术支持，也可以直接联系Abways中国

Click here

>> 针对此靶点的所有抗体产品

>> 针对此靶点的所有兔单抗产品