Cleaved-Caspase 3 p17 Ab - 上海埃必威生物技术有限公司

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Cleaved-Caspase 3 p17 Ab

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Western blot analysis of active Caspase-3 expression in Jurkat cell lysate treated with Camptothecin.

Combination of novel DR5 targeting agonistic scFv antibody TR2-3 with cisplatin shows enhanced synergistic antitumor activity in vitro and in vivo. -Biomedicine & Pharmacotherapy

Immunofluorescent analysis of HepG2 cells, using active Caspase-3 Antibody .

产品简介

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产品简介

Catalog No.

CY5031

Source

Recombinant Rabbit mAb

UniProt ID

P42574

Reactivity

Human

Application

WB;IHC;ICC/IF;IHF

Calculated Mol Weight

17,32 kDa

Observed Mol Weight

17 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

Alternative Names

Apopain precursor; Cysteine protease CPP32; ICE3; CASP-3; CPP32; Caspase-3; SCA-1;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Other

Immunogen

A synthesized peptide derived from human Caspase 3

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Purification

Affinity-chromatography

Concentration

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Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Thiol protease that acts as a major effector caspase involved in the execution phase of apoptosis.Following cleavage and activation by initiator caspases (CASP8, CASP9 and/or CASP10), mediates execution of apoptosis by catalyzing cleavage of many proteins.

引用文献

Cytidine monophosphate kinase is inhibited by the TGF-β signalling pathway through the upregulation of miR-130b-3p in human epithelial ovarian cancer

期刊名称：

CELLULAR SIGNALLING

PMID：

28414100

影响因子：

3.937

应用范围：

检测物种：

Human

发表时间：

2017-04-14

Data on the association of CMPK1 with clinicopathological features and biological effect in human epithelial ovarian cancer

期刊名称：

Data in Brief

PMID：

28560285

影响因子：

应用范围：

检测物种：

Human

发表时间：

2017-05-12

Salidroside induces apoptosis and protective autophagy in human gastric cancer AGS cells through the PI3K/Akt/mTOR pathway

期刊名称：

BIOMEDICINE & PHARMACOTHERAPY

PMID：

31918283

影响因子：

3.743

应用范围：

检测物种：

Human

发表时间：

2019-12-30

Phenols fragment of Veronica ciliata Fisch. ameliorate free radical-induced nonalcoholic fatty liver disease by mediating PI3K/Akt signaling pathway

期刊名称：

JOURNAL OF ETHNOPHARMACOLOGY

PMID：

31978521

影响因子：

3.69

应用范围：

检测物种：

Rat

发表时间：

2020-01-21

Reactive Oxygen Species Mediate 6c-Induced Mitochondrial and Lysosomal Dysfunction, Autophagic Cell Death, and DNA Damage in Hepatocellular Carcinoma

期刊名称：

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

PMID：

34681647

影响因子：

5.924

应用范围：

检测物种：

Human

发表时间：

2021-10-12

Ivermectin induces apoptosis of esophageal squamous cell carcinoma via mitochondrial pathway

期刊名称：

BMC CANCER

PMID：

34876051

影响因子：

4.43

应用范围：

WB,IHC

检测物种：

Human,Mouse

发表时间：

2021-12-07

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CY5031

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

现货

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