Caspase 9 Ab - 上海埃必威生物技术有限公司

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Caspase 9 Ab

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All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.

Western blot analysis of cleaved Caspase-9 Antibody expression in HeLa cell lysate treated with staurosporine.

EMP3, which is regulated by miR-663a, suppresses gallbladder cancer progression via interference with the MAPK/ERK pathway. -Cancer Letters

All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.

产品简介

引用文献

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产品简介

Catalog No.

CY5682

Source

Recombinant Rabbit mAb

UniProt ID

P55211

Reactivity

Human;Mouse

Application

WB;IP

Calculated Mol Weight

46 kDa

Observed Mol Weight

46, 39, 37, 35 kDa

Recommended Dilution

WB 1:1000-1:2000

IP 1:20-1:50

Alternative Names

MCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6; CASP9; Caspase-9; Caspase 9 Dominant Negative;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human Caspase 9

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Purification

Affinity-chromatography

Concentration

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Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates effector caspases caspase-3 (CASP3) or caspase-7 (CASP7). Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).

引用文献

Attenuated Salmonella carrying siRNA-PD-L1 and radiation combinatorial therapy induces tumor regression on HCC through T cell-mediated immuno-enhancement

期刊名称：

Cell Death Discovery

PMID：

37640735

影响因子：

应用范围：

检测物种：

Mouse

发表时间：

2023-08-28

EMP3 as a key downstream target of miR-663a regulation interferes with MAPK/ERK signaling pathway to inhibit gallbladder cancer progression

期刊名称：

CANCER LETTERS

PMID：

37730106

影响因子：

9.7

应用范围：

检测物种：

Human

发表时间：

2023-09-18

MiR-4521 affects the propagation of Cryptosporidium parvum in HCT-8 cells through targeting foxm1 by regulating cell apoptosis

期刊名称：

ACTA TROPICA

PMID：

37913972

影响因子：

2.7

应用范围：

检测物种：

Human

发表时间：

2023-10-31

Nifuroxazide suppresses PD-L1 expression and enhances the efficacy of radiotherapy in hepatocellular carcinoma

期刊名称：

eLife

PMID：

38441416

影响因子：

6.4

应用范围：

WB,ICC/IF

检测物种：

Mouse,Human

发表时间：

2024-03-05

Kojic acid inhibits pig sperm apoptosis and improves capacitated sperm state during liquid preservation at 17°C

期刊名称：

MOLECULAR REPRODUCTION AND DEVELOPMENT

PMID：

38462735

影响因子：

2.7

应用范围：

检测物种：

Pig

发表时间：

2024-03-10

Supplementing Boar Diet with Nicotinamide Mononucleotide Improves Sperm Quality Probably through the Activation of the SIRT3 Signaling Pathway

期刊名称：

Antioxidants

PMID：

38790612

影响因子：

应用范围：

检测物种：

Pig

发表时间：

2024-04-24

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CY5682

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

现货

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