p62 SQSTM1 Ab - 上海埃必威生物技术有限公司

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p62 SQSTM1 Ab

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All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature.

Western blot analysis of p62/SQSTM1 expression in SKBR-3 cell lysate.

Pyrroloquinoline quinine ameliorates doxorubicin-induced autophagy-dependent apoptosis via lysosomal-mitochondrial axis in vascular endothelial cells. -Toxicology

Prostaglandin E1 Inhibited Diabetes-Induced Phenotypic Switching of Vascular Smooth Muscle Cells Through Activating Autophagy. -Cellular Physiology and Biochemistry

MicroRNA-199a acts as a potential suppressor of cardiomyocyte autophagy through targeting Hspa5. -Oncotarget

Immunofluorescent analysis using the Antibody at 1:50 dilution.

Immunofluorescent analysis of Hela cells, using p62/SQSTM1 Antibody.

产品简介

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产品简介

Catalog No.

CY5546

Source

Recombinant Rabbit mAb

UniProt ID

Q13501

Reactivity

Human;Mouse;Rat

Application

WB;ICC/IF;IP;FC

Calculated Mol Weight

48 kDa

Observed Mol Weight

62 kDa

Recommended Dilution

WB 1:1000-1:5000

ICC/IF 1:50-1:200

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

OSIL; Oxidative stress induced like; p60; p62; p62B; Paget disease of bone 3;PDB 3; PDB3;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human Sequestosome 1

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Purification

Affinity-chromatography

Concentration

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Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Molecular adapter required for selective macroautophagy (aggrephagy) by acting as a a bridge between polyubiquitinated proteins and autophagosomes.Promotes the recruitment of ubiquitinated cargo proteins to autophagosomes via multiple domains that bridge proteins and organelles in different steps.

引用文献

Co-delivery of autophagy inhibitor and gemcitabine using a pH-activatable core-shell nanobomb inhibits pancreatic cancer progression and metastasis

期刊名称：

Theranostics

PMID：

34522207

影响因子：

11.556

应用范围：

WB,IHC

检测物种：

Mouse,Human

发表时间：

2021-08-04

Obesity induced Ext1 reduction mediates the occurrence of NAFLD

期刊名称：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

PMID：

34906902

影响因子：

3.575

应用范围：

检测物种：

Human

发表时间：

2021-12-07

Repurposed antipsychotic chlorpromazine inhibits colorectal cancer and pulmonary metastasis by inducing G2/M cell cycle arrest, apoptosis, and autophagy

期刊名称：

CANCER CHEMOTHERAPY AND PHARMACOLOGY

PMID：

35067737

影响因子：

3.288

应用范围：

检测物种：

Human,Mouse

发表时间：

2022-01-24

DDIT3 antagonizes innate immune response to promote bovine alphaherpesvirus 1 replication via the DDIT3-SQSTM1-STING pathway

期刊名称：

Virulence

PMID：

35259065

影响因子：

5.428

应用范围：

检测物种：

Bovine

发表时间：

2022-03-08

Neospora caninum infection activated autophagy of caprine endometrial epithelial cells via mTOR signaling

期刊名称：

VETERINARY PARASITOLOGY

PMID：

35272252

影响因子：

2.821

应用范围：

WB,ICC/IF

检测物种：

Goat

发表时间：

2022-03-04

A neutrophil-mediated carrier regulates tumor stemness by inhibiting autophagy to prevent postoperative triple-negative breast cancer recurrence and metastasis

期刊名称：

Acta Biomaterialia

PMID：

35447368

影响因子：

10.633

应用范围：

检测物种：

Mouse

发表时间：

2022-04-18

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CY5546

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

现货

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