IL6 Mouse mAb
Source: Mouse mAb Catalog No. : BY5001
IL6 Mouse mAb (BY5001)
UniProt:P05231
Application:WB IHC ICC/IF
Reactivity:Human
Source:Mouse mAbhttp://www.abways.cn/showproduct.asp?cid=BY5001
数据表
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UniProt
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Mol Weight20kDa
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Alternative NamesInterleukin-6, B-cell stimulatory factor 2 (BSF-2), CTL differentiation factor (CDF), Hybridoma growth factor, Interferon beta-2 (IFN-beta-2), IFNB2
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ImmunogenA synthesized peptide derived from human IL6
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StorageMouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeMouse IgG1
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ClonalityMonoclonal
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DescriptionCytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the brea own of fats and to improve insulin resistance.Genetic variations in IL6 are associated with susceptibility to rheumatoid arthritis systemic juvenile. An inflammatory articular disorder with systemic-onset beginning before the age of 16. It represents a subgroup of juvenile arthritis associated with severe extraarticular features and occasionally fatal complications. During active phases of the disorder, patients display a typical daily spiking fever, an evanescent macular rash, lymphadenopathy, hepatosplenomegaly, serositis, myalgia and arthritis.
Applications
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ReactivityHuman
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ApplicationWB IHC ICC/IF
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Recommended dilutionWB: 1:1000~1:10000 IHC 1:50~1:500 ICC/IF 1:50~1:500