Histone H3 (mono+di+tri methyl K79) Antibody
Source: Rabbit mAb Catalog No. : CY5483
Histone H3 (mono+di+tri methyl K79) Antibody (CY5483)
UniProt:P68431
Application:WB,IHC
Reactivity:Human,Mouse,Rat
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY5483
数据表
-
UniProt
-
Mol Weight15kDa
-
Alternative NamesH3 histone; HIST1H3A; Histone cluster 1, H3a;H3/l; HIST3H3; H3K79me1; H3K79me2; H3K79me3;
-
ImmunogenA synthesized peptide derived from human Histone H3 (mono+di+tri methyl K79)
-
StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
-
PurificationAffinity-chromatography
-
IsotypeRabbit IgG
-
ClonalityMonoclonal
-
DescriptionH3 Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.
Applications
-
ReactivityHuman,Mouse,Rat
-
ApplicationWB,IHC
-
Recommended dilutionWB 1:500~1:1000 IHC 1:1000~1:2000