Dnmt3b Antibody
Source: Rabbit mAb Catalog No. : CY5006
Dnmt3b Antibody (CY5006)
UniProt:Q9UBC3
Application:WB,ICC/IF
Reactivity:Human,Mouse,Rat
Source:Rabbit mAbhttp://www.abways.cn/showproduct.asp?cid=CY5006
数据表
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UniProt
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Mol Weight96kDa
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Alternative NamesDnmt3b; DNA methyltransferase HsaIIIB; DNMT3B;
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ImmunogenA synthesized peptide derived from human Dnmt3b
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StorageRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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PurificationAffinity-chromatography
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IsotypeRabbit IgG
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ClonalityMonoclonal
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DescriptionRequired for genome wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. May preferentially methylates nucleosomal DNA within the nucleosome core region. May function as transcriptional co-repressor by associating with CBX4 and independently of DNA methylation. Seems to be involved in gene silencing (By similarity).
Applications
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ReactivityHuman,Mouse,Rat
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ApplicationWB,ICC/IF
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Recommended dilutionWB 1:500~1:2000 ICC/IF 1:50~1:200
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All lanes use the Antibody at 1:1W dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:1W dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:1W dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:1W dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:1W dilution for 1 hour at room temperature. -
All lanes use the Antibody at 1:1W dilution for 1 hour at room temperature. -
Western blot analysis of Dnmt3b expression in (1) A549 cell lysate; (2) A431 cell lysate.
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